Air China will start flying from Chengdu to Bangkok to cater to Chinese tourists visiting the kingdom.
The flagship carrier's maiden direct flight from the capital of the Sichuan province to Bangkok will be on Feb 12.
The Thai capital is among top destinations for Chinese travellers, the airline said in a statement.
"Bangkok is famed for its culinary prowess, gorgeous islands, historical pagodas and exciting nightlife, making the city a popular choice for tourists," it said.
About 9.8 million tourists from China came to Thailand last year, a 12% rise from 8.7 million in 2016, according to Tourism and Sports Ministry figures. Chinese tourists topped the rankings of foreigners taking vacations in the country.
The Bangkok-Chengdu route is already offered by several full-service and low-cost airlines, including Thai Airways International, Thai AirAsia, China Southern and Thai Lion Air.
The central Chinese city has a population of more than 14 million.