Chinese clone monkeys, but no humans yet

Cloned monkeys Zhong Zhong and Hua Hua are seen at the non-human primate facility at the Chinese Academy of Sciences in Shanghai on Tuesday. (China Daily via Reuters)
Cloned monkeys Zhong Zhong and Hua Hua are seen at the non-human primate facility at the Chinese Academy of Sciences in Shanghai on Tuesday. (China Daily via Reuters)

LONDON: Chinese scientists have cloned monkeys using the same technique that produced Dolly the sheep two decades ago, breaking a technical barrier that could open the door to copying humans.

Zhong Zhong and Hua Hua, two identical long-tailed macaques, were born eight and six weeks ago, making them the first primates -- the order of mammals that includes monkeys, apes and humans -- to be cloned from a non-embryonic cell.

It was achieved through a process called somatic cell nuclear transfer (SCNT), which involves transferring the nucleus of a cell, which includes its DNA, into an egg which has had its nucleus removed.

Researchers at the Chinese Academy of Sciences Institute of Neuroscience in Shanghai said their work should be a boon to medical research by making it possible to study diseases in populations of genetically uniform monkeys.

But it also brings the feasibility of cloning to the doorstep of our own species.

"Humans are primates. So [for] the cloning of primate species, including humans, the technical barrier is now broken," Muming Poo, who helped supervise the programme at the institute, told reporters in a conference call.

"The reason ... we broke this barrier is to produce animal models that are useful for medicine, for human health. There is no intention to apply this method to humans."

The two newborns are now being bottle fed and are growing normally. The researchers said they expect more macaque clones to be born over the coming months.

Since Dolly the sheep was born in Scotland in 1996, scientists have successfully used SCNT to clone more than 20 other species, including cows, pigs, dogs, rabbits, rats and mice.

Similar work in primates, however, had always failed, leading some experts to wonder if primates were resistant.

The new research shows that is not the case. The Chinese team succeeded, after many attempts. In all, it took 127 eggs to produce two live macaque births.

"It remains a very inefficient and hazardous procedure," said Robin Lovell-Badge, a cloning expert at the Francis Crick Institute in London, who was not involved in the Chinese work.

"The work in this paper is not a stepping-stone to establishing methods for obtaining live born human clones. This clearly remains a very foolish thing to attempt."

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Vocabulary

  • barrier (noun): anything that prevents people from doing something - อุปสรรค
  • boon (noun): something good and useful that you get; a benefit - สิ่งที่เป็นประโยชน์, สิ่งที่ช่วยอำนวยความสะดวก
  • clone: a person or thing that seems to be an exact copy of another - โคลน, สำเนา
  • embryonic (adj): of an embryo; in an early stage of development - ได้จากตัวอ่อนระยะแรก; ในขั้นต้น,เป็นตัวอ่อน,เพิ่งเริ่มก่อตัว
  • feasibility: the possibility that something can be achieved - ความเป็นไปได้
  • foolish: not showing good sense or judgement - โง่
  • genetically (adj): relating to genes, or to the study of genes - เกี่ยวกับพันธศาสตร์,ยีน
  • hazardous: dangerous, especially to people’s health or safety - ที่เป็นอันตราย
  • identical: exactly the same, or very similar - เหมือนกัน, แบบเดียวกัน
  • macaques (noun): a type of monkey that lives in Africa and Asia - ลิงแสม
  • nucleus: the central part of a cell in the body of a living thing; the part that controls the operation and reproduction of the cell -
  • resistant (adj): not harmed or affected by something - ต้าน,ต่อต้าน, ต้านทาน
  • uniform: when everything is the same; without differences -
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