Buriram United and Muang Thong United will renew their rivalry when they meet in the FA Cup quarter-finals following Monday's draw.
Bangkok United will face Ratchaburi and Chonburi will take on Trat in the other two all-Thai League 1 clashes.
T1 champions Chiang Rai United were handed a relatively comfortable assignment as they will be up against T3 side Muangkan United.
The quarter-finals will be played on April 3, the semi-finals on April 7, and the final on April 11.
Buriram and Muang Thong are the country's most successful teams in recent memory with both winning several top league titles.
But while Buriram have won the FA Cup four times, the Kirins have never lifted the trophy, finishing runners-up three times.
Thunder Castle coach Alexandre Gama will be out for revenge after being sacked by Muang Thong last year and replaced by former Muang Thong star Mario Gjurovski.
In their meeting in T1 last year, Gjurovski's men, led by in-form striker Willian Popp, beat Gama's team 3-2 at Chang Arena.
Buriram knocked out holders Port in the previous round, while Muang Thong stunned T1 leaders BG Pathum United on the way to the quarter-finals.
The event is more important this term as the champions will earn a direct entry to the 2022 AFC Champions League group stage, along with the T1 winners.
Meanwhile, both Buriram and Muang Thong will be in action in T1 today.
Second-ranked Buriram should have few problems when they host relegation strugglers Trat who appear to be heading to the second tier.
Fourth-placed Muang Thong face a tricky match against Police Tero.