The sale and distribution of alcoholic drinks is banned for the 24 hours from midnight on Saturday until midnight Sunday.
Deputy police spokesman Pol Col Kritsana Pattanacharoen on Friday told media that the ban was to honour the last day of Buddhist Lent and memorial day of the late HM King Bhumibol Adulyadej.
He said police enforcing the ban would check entertainment venues, department storesand shops at train stations and petrol stations.
Sellers and drinkers would be penalised if caught, he said.
Penalties for violating Section 59 of Alcohol Beverage Control Act are up to six-months imprisonment and/or a maximum fine of 10,000 baht.